Muhammad Rafi Uthmani (Urdu: محمد رفیع عثمانی) is a Muslim scholar in the Islamic Republic of Pakistan. He is serving as the President of Darul Uloom Karachi. He is the son of the late Muhammad Shafi Usmani, the founder of Darul Ulum Karachi. He is recognized for his knowledge in fiqh, hadith, and tafsir. He has authored a large number of books in Urdu, as well as some notable treatises in Arabic. He is the brother of another notable Islamic scholar, Mufti Muhammad Taqi Usmani and Maulana Wali Razi. Mufti Sahab is also a member of Jamiatul Ulama USA.